Synonyms : Amimycin, Matromycin, PA 105
Specifications
CAS # : 3922-90-5
Molecular Formula : C35H61NO12
Molecular Weight : 687.9
Source : Streptomyces sp.
Appearance : White solid
Purity : >95% by HPLC
Long Term Storage : -20°C
Solubility : Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Application Notes
Oleandomycin is a 16-membered macrocyclic lactone, discovered in the 1950s, with broad spectrum antibacterial activity. Oleandomycin was developed as a human pharmaceutical but was regarded as less active than comparable products such as erythromycin and is today only available in combination with other antibiotics.
References
1. Oleandomycin (PA-105). II. Chemical characterization. Els H. et al. JACS 1958, 80, 3777.
2. The structure of oleandomycin Hochstein F.A. et al. JACS 1960, 82, 3225.