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Actinomycin D/放线菌素D

产品编号:BIA-A1185
产品规格:25mg/100mg
价  格:1800.00/6300.00
供 应 商:BioAustralis
库  存:常年库存
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Actinomycin D is the most studied member of a family of unique
bicyclic depsipeptides produced by several Streptomyces species.
The depsipeptides are linked by a heterocyclic benzoxazone
"anchor" that gives the metabolites a highly distinctive red/orange
colour. Actinomycin D exhibits potent antibiotic and antitumor
activity acting by DNA intercalation leading to the inhibition of
nucleic acid synthesis. Tumor cell death has been demonstrated to
occur by apoptosis.
CAS Number:  50-76-0
Molecular Formula:  C62H86N12O16
 Molecular Weight: 1255.4
Source:  from Streptomyces sp. 
Purity: >99% by HPLC 


放线菌素D (Actinomycin D

货号: BIA-A1185   包装规格: 25 mg, 100 mg

放线菌素D是特殊的双环酯肽家族中研究最多的一种,由一些链霉菌分泌。这类酯肽通过一个杂环benzoxazone单位相连接,相应的代谢产物带有很特殊的红色/橙色。放线菌素D通过DNA嵌入可以抑制核酸的合成,因此有着很强的抗生素及抗癌活性。癌细胞的死亡已经通过细胞凋亡试验得到了验证。

CAS 号: 50-76-0

分子式: C62H86N12O16

分子量: 1255.4

来源: 来自于链霉菌属

纯度: >99% by HPLC

 

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